Healthcare-associated infections (HAIs) are infections that patients acquire while receiving medical treatment in a healthcare facility. These infections can occur in hospitals, long-term care facilities, outpatient clinics, and other healthcare settings. HAIs can be caused by a variety of pathogens, including bacteria, viruses, and fungi, and they can lead to additional illness, prolonged hospital stays, increased healthcare costs, and in severe cases, death. Prevention of HAIs is a critical aspect of healthcare delivery, as these infections are often preventable with proper infection control measures. Healthcare facilities must implement protocols for hand hygiene, proper use of personal protective equipment, environmental cleaning, and other measures to reduce the risk of HAIs. Research in the area of healthcare-associated infections focuses on understanding the epidemiology of these infections, identifying risk factors for acquisition, developing new prevention strategies, and evaluating the effectiveness of infection control measures. By studying HAIs and implementing evidence-based interventions, healthcare providers can work towards reducing the burden of these infections on patients, healthcare workers, and the healthcare system as a whole.